Desflurane
Very rapid onset and offset characterise desflurane, a volatile inhalational anaesthetic used to maintain general anaesthesia, and that kinetic profile permits quick emergence in the recovery room. Low blood solubility underlies the speed with which alveolar and brain concentrations equilibrate and then fall. Its high volatility and low boiling point mean it cannot be given from a conventional vaporiser and requires a specialised heated device. Two drawbacks temper its use: the vapour irritates the airway, and the molecule is a potent greenhouse gas, a property that has brought the environmental cost of inhalational anaesthesia under scrutiny. The compound is C3H2F6O with a molecular weight near 168.0 g/mol.
A volatile inhalation anesthetic used to maintain general anesthesia during surgery, known for its very rapid onset and offset, allowing for quick awakening in the recovery room. It is delivered via a specialized vaporizer due to its high volatility and low boiling point. It can irritate the airways and is a potent greenhouse gas, raising concerns about its environmental impact.
分子量
168.0400 g/mol
LogP
2.60
TPSA
9.20 Ų
Lipinski 五规则
符合
治疗领域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
二维结构
Cite this structure
Embed this structure
SMILES
FC(F)OC(F)C(F)(F)F
InChI
InChI=1S/C3H2F6O/c4-1(3(7,8)9)10-2(5)6/h1-2H
Molecular Formula
C3H2F6O
HBD / HBA
- / 7
可旋转键数
2
重原子数
10
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
A volatile inhalation anesthetic used to maintain general anesthesia during surgery, known for its very rapid onset and offset, allowing for quick awakening in the recovery room. It is delivered via a specialized vaporizer due to its high volatility and low boiling point. It can irritate the airways and is a potent greenhouse gas, raising concerns about its environmental impact.
Yes, Desflurane is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200733. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 42113. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-08-20.
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