Desoxycorticosterone Pivalate

CHEMBL1200592 Phase 4 已批准 Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
414.6 g/mol
LogP
4.5
Phase
4

The pivalate ester of desoxycorticosterone providing prolonged mineralocorticoid activity after injection, used for adrenal insufficiency. The long-acting ester requires less frequent injections compared to other forms.

分子量

414.6000 g/mol

LogP

4.50

TPSA

60.40 Ų

Lipinski 五规则

符合

作用机制

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

二维结构

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SMILES

CC(C)(C)C(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

InChI=1S/C26H38O4/c1-24(2,3)23(29)30-15-22(28)21-9-8-19-18-7-6-16-14-17(27)10-12-25(16,4)20(18)11-13-26(19,21)5/h14,18-21H,6-13,15H2,1-5H3/t18-,19-,20-,21+,25-,26-/m0/s1

Molecular Formula

C26H38O4

HBD / HBA

- / 4

可旋转键数

5

重原子数

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

The pivalate ester of desoxycorticosterone providing prolonged mineralocorticoid activity after injection, used for adrenal insufficiency. The long-acting ester requires less frequent injections compared to other forms.

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Yes, Desoxycorticosterone Pivalate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200592. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11876263. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.