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Dexpanthenol

CHEMBL1200979 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
205.2 g/mol
LogP
-0.9
Phase
4

The d-isomer of pantothenol (provitamin B5) that is converted to pantothenic acid in the body, used topically as a moisturizer and wound-healing agent, and parenterally to stimulate bowel motility after surgery. It supports synthesis of coenzyme A and promotes skin barrier function.

分子量

205.2500 g/mol

LogP

-0.90

TPSA

89.80 Ų

Lipinski 五规则

符合

治疗领域

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Gastroesophageal Reflux Disease Systemic Lupus Erythematosus Breast Cancer Atopic Dermatitis Chronic Pain Prostate Cancer Colorectal Cancer

作用机制

Forms an occlusive barrier on the skin surface, reducing transepidermal water loss and protecting the underlying tissue from external irritants.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Forms an occlusive barrier on the skin surface, reducing transepidermal water loss and protecting the underlying tissue from external irritants.

二维结构

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC(C)(CO)[C@@H](O)C(=O)NCCCO

                

                

                
                

                    
InChI

                    
InChI=1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C9H19NO4

                    

                    
                    

                        
HBD / HBA

                        
4 / 4

                    

                    
                    

                        
可旋转键数

                        
6

                    

                    
                    
                    

                        
重原子数

                        
14

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
The d-isomer of pantothenol (provitamin B5) that is converted to pantothenic acid in the body, used topically as a moisturizer and wound-healing agent, and parenterally to stimulate bowel motility after surgery. It supports synthesis of coenzyme A and promotes skin barrier function.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Forms an occlusive barrier on the skin surface, reducing transepidermal water loss and protecting the underlying tissue from external irritants.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Dexpanthenol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200979.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 131204.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.