Dextroamphetamine Adipate

Central nervous system stimulation by dextroamphetamine follows from increased dopaminergic and noradrenergic signalling, and the adipate is one salt form in which the active moiety is supplied. Attention deficit hyperactivity disorder and narcolepsy are the two established indications, conditions in which enhanced catecholamine transmission improves attentional control or wakefulness respectively. The salt form influences pharmaceutical properties rather than the receptor pharmacology, which remains that of the parent amphetamine enantiomer. Its recorded formula is C15H23NO4 with a molecular weight near 281.4 g/mol. The agent is approved as a small molecule and has completed the final phase of clinical development within the stimulant class.

SMILES

C[C@H](N)Cc1ccccc1.O=C(O)CCCCC(=O)O

InChI

InChI=1S/C9H13N.C6H10O4/c1-8(10)7-9-5-3-2-4-6-9;7-5(8)3-1-2-4-6(9)10/h2-6,8H,7,10H2,1H3;1-4H2,(H,7,8)(H,9,10)/t8-;/m0./s1