Dinoprostone

CHEMBL548 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

352.5 g/mol

LogP

2.8

Phase

4

A synthetic prostaglandin E2 used to ripen the cervix and induce labor in pregnant women at or near term. It acts on prostaglandin receptors to stimulate uterine contractions and soften the cervix. It is available as vaginal inserts, gels, and suppositories, and must be used in a monitored hospital setting due to the risk of uterine hyperstimulation.

分子量

352.5000 g/mol

LogP

2.80

TPSA

94.80 Å²

Lipinski 五规则

符合

治疗领域

Endometriosis Pain Management Asthma Chronic Obstructive Pulmonary Disease Migraine Obesity Lymphoma Type 2 Diabetes Hypertension Chronic Pain Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O

InChI

InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1

Molecular Formula

C20H32O5

HBD / HBA

3 / 5

可旋转键数

12

重原子数

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

A synthetic prostaglandin E2 used to ripen the cervix and induce labor in pregnant women at or near term. It acts on prostaglandin receptors to stimulate uterine contractions and soften the cervix. It is available as vaginal inserts, gels, and suppositories, and must be used in a monitored hospital setting due to the risk of uterine hyperstimulation.

Yes, Dinoprostone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL548. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5280360. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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结构

快速数据

分子式: C20H32O5
同义词: 2

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.