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Elagolix

CHEMBL1208155 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
631.6 g/mol
LogP
2.6
Phase
4

This medication works by reducing the production of certain hormones that stimulate the growth of endometrial tissue outside the uterus. It helps relieve the pain associated with endometriosis.

分子量

631.6000 g/mol

LogP

2.60

TPSA

99.20 Ų

Lipinski 五规则

不符合

治疗领域

Endometriosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

                    
COc1cccc(-c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](NCCCC(=O)O)c3ccccc3)c2=O)c1F

                

                

                
                

                    
InChI

                    
InChI=1S/C32H30F5N3O5/c1-19-28(21-11-6-14-26(45-2)29(21)34)30(43)40(18-25(20-9-4-3-5-10-20)38-16-8-15-27(41)42)31(44)39(19)17-22-23(32(35,36)37)12-7-13-24(22)33/h3-7,9-14,25,38H,8,15-18H2,1-2H3,(H,41,42)/t25-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C32H30F5N3O5

                    

                    
                    

                        
HBD / HBA

                        
2 / 11

                    

                    
                    

                        
可旋转键数

                        
12

                    

                    
                    
                    

                        
重原子数

                        
45

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
This medication works by reducing the production of certain hormones that stimulate the growth of endometrial tissue outside the uterus. It helps relieve the pain associated with endometriosis.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Elagolix is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1208155.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11250647.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.