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Esomeprazole Sodium

CHEMBL1200470 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
367.4 g/mol
LogP
—
Phase
4

The sodium salt form of esomeprazole, this proton pump inhibitor is formulated for intravenous use to reduce stomach acid in hospitalized patients. It works by blocking the enzyme responsible for acid secretion.

分子量

367.4000 g/mol

TPSA

81.50 Ų

治疗领域

Gastroesophageal Reflux Disease

作用机制

S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

二维结构

SVG PNG

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SMILES

                    
COc1ccc2[n-]c([S@@+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C17H18N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3;/q-1;+1/t24-;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C17H18N3NaO3S

                    

                    
                    

                        
HBD / HBA

                        
- / 7

                    

                    
                    

                        
可旋转键数

                        
5

                    

                    
                    
                    

                        
重原子数

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
The sodium salt form of esomeprazole, this proton pump inhibitor is formulated for intravenous use to reduce stomach acid in hospitalized patients. It works by blocking the enzyme responsible for acid secretion.

                        

                    

                    

                    

                    
                    

                        
                        

                            
S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Esomeprazole Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200470.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23674541.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.