Ethosuximide
This anticonvulsant medication works by blocking a specific type of calcium channel in brain cells that is responsible for the abnormal electrical activity causing absence seizures. It is the drug of choice for absence epilepsy.
分子量
141.1700 g/mol
LogP
0.40
TPSA
46.20 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of …
二维结构
Cite this structure
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SMILES
CCC1(C)CC(=O)NC1=O
InChI
InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
Molecular Formula
C7H11NO2
HBD / HBA
1 / 2
可旋转键数
1
重原子数
10
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
This anticonvulsant medication works by blocking a specific type of calcium channel in brain cells that is responsible for the abnormal electrical activity causing absence seizures. It is the drug of choice for absence epilepsy.
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Yes, Ethosuximide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL696. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3291. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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