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Fentanyl Hydrochloride

CHEMBL1201159 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
372.9 g/mol
LogP
—
Phase
4

This medication is a salt form of fentanyl, a powerful opioid pain reliever used for severe or chronic pain that has not responded to other treatments. It works by binding to opioid receptors in the brain to block pain signals. Due to its high potency, it carries a significant risk of dependence and overdose.

分子量

372.9000 g/mol

TPSA

23.60 Ų

治疗领域

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Chronic Kidney Disease Obesity Hypertension Breast Cancer Chronic Pain Heart Failure Prostate Cancer Colorectal Cancer

作用机制

Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

二维结构

SVG PNG

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SMILES

                    
CCC(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C22H28N2O.ClH/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19;/h3-12,21H,2,13-18H2,1H3;1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H29ClN2O

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
可旋转键数

                        
6

                    

                    
                    
                    

                        
重原子数

                        
26

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
This medication is a salt form of fentanyl, a powerful opioid pain reliever used for severe or chronic pain that has not responded to other treatments. It works by binding to opioid receptors in the brain to block pain signals. Due to its high potency, it carries a significant risk of dependence and overdose.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Fentanyl Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201159.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 83932.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.