Finerenone
This medication blocks a hormone receptor called the mineralocorticoid receptor, reducing inflammation and scarring in the heart and kidneys. It is used to slow the progression of chronic kidney disease in adults with type 2 diabetes and to reduce the risk of heart failure.
分子量
378.4000 g/mol
LogP
2.40
TPSA
110.00 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.
二维结构
Cite this structure
Embed this structure
SMILES
CCOc1ncc(C)c2c1[C@H](c1ccc(C#N)cc1OC)C(C(N)=O)=C(C)N2
InChI
InChI=1S/C21H22N4O3/c1-5-28-21-18-17(14-7-6-13(9-22)8-15(14)27-4)16(20(23)26)12(3)25-19(18)11(2)10-24-21/h6-8,10,17,25H,5H2,1-4H3,(H2,23,26)/t17-/m1/s1
Molecular Formula
C21H22N4O3
HBD / HBA
2 / 6
可旋转键数
5
重原子数
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
This medication blocks a hormone receptor called the mineralocorticoid receptor, reducing inflammation and scarring in the heart and kidneys. It is used to slow the progression of chronic kidney disease in adults with type 2 diabetes and to reduce the risk of heart failure.
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.
Yes, Finerenone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2181927. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 60150535. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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