Gemfibrozil
A fibrate medication used to lower triglyceride levels and raise HDL (good) cholesterol by activating receptors in the liver that regulate fat metabolism. It is used in patients at risk for cardiovascular disease or pancreatitis due to very high triglycerides, and may also benefit patients with chronic kidney disease affecting lipid levels. Regular monitoring of liver function and muscle-related symptoms is recommended during treatment.
分子量
250.3300 g/mol
LogP
3.80
TPSA
46.50 Ų
Lipinski 五规则
符合
治疗领域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
二维结构
Cite this structure
Embed this structure
SMILES
Cc1ccc(C)c(OCCCC(C)(C)C(=O)O)c1
InChI
InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)
Molecular Formula
C15H22O3
HBD / HBA
1 / 3
可旋转键数
6
重原子数
18
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
A fibrate medication used to lower triglyceride levels and raise HDL (good) cholesterol by activating receptors in the liver that regulate fat metabolism. It is used in patients at risk for cardiovascular disease or pancreatitis due to very high triglycerides, and may also benefit patients with chronic kidney disease affecting lipid levels. Regular monitoring of liver function and muscle-related symptoms is recommended during treatment.
Yes, Gemfibrozil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL457. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3463. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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