Hydroxyprogesterone Caproate
This synthetic progestogen is given by weekly injection to reduce the risk of recurrent preterm birth in women with a history of spontaneous preterm delivery. It works by supporting uterine quiescence and preventing premature contractions. It is also used in some hormone therapy protocols for gynecological conditions.
分子量
428.6000 g/mol
LogP
5.70
TPSA
60.40 Ų
Lipinski 五规则
符合
治疗领域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
二维结构
Cite this structure
Embed this structure
SMILES
CCCCCC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
InChI
InChI=1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1
Molecular Formula
C27H40O4
HBD / HBA
- / 4
可旋转键数
7
重原子数
31
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
This synthetic progestogen is given by weekly injection to reduce the risk of recurrent preterm birth in women with a history of spontaneous preterm delivery. It works by supporting uterine quiescence and preventing premature contractions. It is also used in some hormone therapy protocols for gynecological conditions.
Yes, Hydroxyprogesterone Caproate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200848. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 169870. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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