Ixekizumab
This interleukin-17A (IL-17A) antagonist monoclonal antibody is used to treat moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. By blocking IL-17A, a key driver of the inflammatory skin and joint lesions in these conditions, it significantly reduces plaques, skin clearing, and joint inflammation. It is self-administered by subcutaneous injection.
治疗领域
作用机制
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
This interleukin-17A (IL-17A) antagonist monoclonal antibody is used to treat moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. By blocking IL-17A, a key driver of the inflammatory skin and joint lesions in these conditions, it significantly reduces plaques, skin clearing, and joint inflammation. It is self-administered by subcutaneous injection.
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Yes, Ixekizumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1743034. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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