Lutetium Lu-177 Vipivotide Tetraxetan
A PSMA-targeted radioligand therapy approved for prostate-specific membrane antigen-positive metastatic castration-resistant prostate cancer. It delivers targeted radiation to prostate cancer cells by binding to PSMA, a protein highly expressed on prostate cancer cells.
分子量
1216.1000 g/mol
TPSA
374.00 Ų
治疗领域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
二维结构
Cite this structure
Embed this structure
SMILES
C1CC(CCC1CNC(=O)CN2CCN(CCN(CCN(CC2)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])C(=O)N[C@@H](CC3=CC4=CC=CC=C4C=C3)C(=O)NCCCC[C@@H](C(=O)O)NC(=O)N[C@@H](CCC(=O)O)C(=O)O.[177Lu+3]
InChI
InChI=1S/C49H71N9O16.Lu/c59-40(28-55-17-19-56(29-42(62)63)21-23-58(31-44(66)67)24-22-57(20-18-55)30-43(64)65)51-27-32-8-12-35(13-9-32)45(68)52-39(26-33-10-11-34-5-1-2-6-36(34)25-33)46(69)50-16-4-3-7-37(47(70)71)53-49(74)54-38(48(72)73)14-15-41(60)61;/h1-2,5-6,10-11,25,32,35,37-39H,3-4,7-9,12-24,26-31H2,(H,50,69)(H,51,59)(H,52,68)(H,60,61)(H,62,63)(H,64,65)(H,66,67)(H,70,71)(H,72,73)(H2,53,54,74);/q;+3/p-3/t32?,35?,37-,38-,39-;/m0./s1/i;1+2
Molecular Formula
C49H68LuN9O16
HBD / HBA
8 / 20
可旋转键数
24
重原子数
75
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
A PSMA-targeted radioligand therapy approved for prostate-specific membrane antigen-positive metastatic castration-resistant prostate cancer. It delivers targeted radiation to prostate cancer cells by binding to PSMA, a protein highly expressed on prostate cancer cells.
Yes, Lutetium Lu-177 Vipivotide Tetraxetan is an approved drug. It has reached clinical phase 4. It is classified as a Protein.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594406. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 122706785. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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