Mannitol
An osmotic agent used intravenously to reduce elevated pressure in the brain and eyes, and as an inhaled powder to test for airway hyperresponsiveness in asthma diagnosis. It is also used orally as a laxative and sweetener in some formulations.
分子量
182.1700 g/mol
LogP
-3.10
TPSA
121.00 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.
二维结构
Cite this structure
Embed this structure
SMILES
OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
Molecular Formula
C6H14O6
HBD / HBA
6 / 6
可旋转键数
5
重原子数
12
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
An osmotic agent used intravenously to reduce elevated pressure in the brain and eyes, and as an inhaled powder to test for airway hyperresponsiveness in asthma diagnosis. It is also used orally as a laxative and sweetener in some formulations.
Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.
Yes, Mannitol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL689. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6251. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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