Maprotiline Hydrochloride

CHEMBL1237135 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

313.9 g/mol

LogP

—

Phase

4

A hydrochloride salt form of maprotiline, a tetracyclic antidepressant used to treat depression and anxiety by increasing norepinephrine activity in the brain.

分子量

313.9000 g/mol

TPSA

12.00 Å²

治疗领域

Schizophrenia Generalized Anxiety Disorder

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

CNCCCC12CCC(c3ccccc31)c1ccccc12.Cl

InChI

InChI=1S/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H

Molecular Formula

C20H24ClN

HBD / HBA

2 / 1

可旋转键数

4

重原子数

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

A hydrochloride salt form of maprotiline, a tetracyclic antidepressant used to treat depression and anxiety by increasing norepinephrine activity in the brain.

Yes, Maprotiline Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1237135. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71478. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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结构

快速数据

分子式: C20H24ClN

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.