Meloxicam
An NSAID that selectively inhibits COX-2 to reduce pain and inflammation from osteoarthritis, rheumatoid arthritis, and juvenile arthritis, with a somewhat lower risk of gastrointestinal side effects compared to non-selective NSAIDs. It is taken once daily due to its long half-life.
分子量
351.4000 g/mol
LogP
3.00
TPSA
136.00 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
二维结构
Cite this structure
Embed this structure
SMILES
Cc1cnc(NC(=O)C2=C(O)c3ccccc3S(=O)(=O)N2C)s1
InChI
InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
Molecular Formula
C14H13N3O4S2
HBD / HBA
2 / 7
可旋转键数
2
重原子数
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
An NSAID that selectively inhibits COX-2 to reduce pain and inflammation from osteoarthritis, rheumatoid arthritis, and juvenile arthritis, with a somewhat lower risk of gastrointestinal side effects compared to non-selective NSAIDs. It is taken once daily due to its long half-life.
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Yes, Meloxicam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL599. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 54677470. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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