Neomycin
This aminoglycoside antibiotic is used topically on the skin to prevent infection in minor cuts, burns, and wounds, and can also be taken orally to reduce bacteria in the intestines before surgery. It works by stopping bacteria from making the proteins they need to survive.
分子量
614.6000 g/mol
LogP
-9.00
TPSA
353.00 Ų
Lipinski 五规则
不符合
治疗领域
作用机制
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
SMILES
C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N
InChI
InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
Molecular Formula
C23H46N6O13
HBD / HBA
13 / 19
可旋转键数
9
重原子数
42
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
This aminoglycoside antibiotic is used topically on the skin to prevent infection in minor cuts, burns, and wounds, and can also be taken orally to reduce bacteria in the intestines before surgery. It works by stopping bacteria from making the proteins they need to survive.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Neomycin is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989751. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 8378. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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