Pentetate Calcium Trisodium
A chelating agent (calcium DTPA) used to treat internal contamination with plutonium, americium, and curium by accelerating their elimination from the body through the urine. It works by forming stable complexes with radioactive heavy metals, facilitating their excretion.
分子量
497.3500 g/mol
TPSA
210.00 Ų
治疗领域
作用机制
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
二维结构
Cite this structure
Embed this structure
SMILES
O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CCN(CC(=O)[O-])CC(=O)[O-].[Ca+2].[Na+].[Na+].[Na+]
InChI
InChI=1S/C14H23N3O10.Ca.3Na/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;;;/q;+2;3*+1/p-5
Molecular Formula
C14H18CaN3Na3O10
HBD / HBA
- / 13
可旋转键数
11
重原子数
31
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
A chelating agent (calcium DTPA) used to treat internal contamination with plutonium, americium, and curium by accelerating their elimination from the body through the urine. It works by forming stable complexes with radioactive heavy metals, facilitating their excretion.
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Yes, Pentetate Calcium Trisodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200945. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 25513. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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