Peramivir
A neuraminidase inhibitor used as a single-dose intravenous treatment for uncomplicated influenza in adults and children, particularly when oral agents cannot be used. It blocks the influenza neuraminidase enzyme, preventing new virus particles from being released from infected cells.
分子量
328.4100 g/mol
LogP
0.00
TPSA
151.00 Ų
Lipinski 五规则
符合
作用机制
Inhibits viral neuraminidase, preventing the release of newly formed virus particles from infected cells and limiting viral spread within the respiratory tract.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits viral neuraminidase, preventing the release of newly formed virus particles from infected cells and limiting viral spread within the respiratory tract.
二维结构
Cite this structure
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SMILES
CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@@H](C(=O)O)C[C@H]1NC(=N)N.O.O.O
InChI
InChI=1S/C15H28N4O4.3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0.../s1
Molecular Formula
C15H28N4O4
HBD / HBA
5 / 5
可旋转键数
7
重原子数
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
A neuraminidase inhibitor used as a single-dose intravenous treatment for uncomplicated influenza in adults and children, particularly when oral agents cannot be used. It blocks the influenza neuraminidase enzyme, preventing new virus particles from being released from infected cells.
Inhibits viral neuraminidase, preventing the release of newly formed virus particles from infected cells and limiting viral spread within the respiratory tract.
Yes, Peramivir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989402. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 154234. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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