Phenolphthalein

CHEMBL63857 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

318.3 g/mol

LogP

3.6

Phase

4

Phenolphthalein is a stimulant laxative that was historically used for the relief of constipation by irritating the colonic mucosa to stimulate peristalsis and reduce water absorption. It has been withdrawn from most over-the-counter markets due to evidence of carcinogenicity in animal studies, with concerns about its potential association with bladder and breast cancer.

分子量

318.3000 g/mol

LogP

3.60

TPSA

66.80 Å²

Lipinski 五规则

符合

治疗领域

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Breast Cancer Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

Cite this structure

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SMILES

O=C1OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21

InChI

InChI=1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H

Molecular Formula

C20H14O4

HBD / HBA

2 / 4

可旋转键数

2

重原子数

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Phenolphthalein is a stimulant laxative that was historically used for the relief of constipation by irritating the colonic mucosa to stimulate peristalsis and reduce water absorption. It has been withdrawn from most over-the-counter markets due to evidence of carcinogenicity in animal studies, with concerns about its potential association with bladder and breast cancer.

Yes, Phenolphthalein is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL63857. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4764. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C20H14O4
同义词: 2

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.