Phenylbutanoic Acid

CHEMBL1469 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

164.2 g/mol

LogP

2.4

Phase

4

Phenylbutanoic acid (4-phenylbutyric acid) is a short-chain fatty acid derivative that acts as a chemical chaperone and histone deacetylase inhibitor with multiple pharmacological actions including reduction of endoplasmic reticulum stress. It is used clinically as adjunctive therapy for urea cycle disorders and is under investigation for various conditions including cancer and neurodegenerative diseases.

分子量

164.2000 g/mol

LogP

2.40

TPSA

37.30 Å²

Lipinski 五规则

符合

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

O=C(O)CCCc1ccccc1

InChI

InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)

Molecular Formula

C10H12O2

HBD / HBA

1 / 2

可旋转键数

4

重原子数

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Phenylbutanoic acid (4-phenylbutyric acid) is a short-chain fatty acid derivative that acts as a chemical chaperone and histone deacetylase inhibitor with multiple pharmacological actions including reduction of endoplasmic reticulum stress. It is used clinically as adjunctive therapy for urea cycle disorders and is under investigation for various conditions including cancer and neurodegenerative diseases.

Yes, Phenylbutanoic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1469. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4775. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C10H12O2

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.