Pimavanserin

CHEMBL2111101 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

427.6 g/mol

LogP

4.5

Phase

4

Used to treat hallucinations and delusions that occur in people with Parkinson's disease psychosis by selectively blocking certain serotonin receptors in the brain without affecting dopamine pathways. This targeted approach makes it particularly suitable for Parkinson's patients who cannot tolerate medications that block dopamine.

分子量

427.6000 g/mol

LogP

4.50

TPSA

44.80 Å²

Lipinski 五规则

符合

治疗领域

Alzheimer's Disease Parkinson's Disease Schizophrenia Insomnia Major Depressive Disorder

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

CC(C)COc1ccc(CNC(=O)N(Cc2ccc(F)cc2)C2CCN(C)CC2)cc1

InChI

InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)

Molecular Formula

C25H34FN3O2

HBD / HBA

1 / 4

可旋转键数

8

重原子数

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Used to treat hallucinations and delusions that occur in people with Parkinson's disease psychosis by selectively blocking certain serotonin receptors in the brain without affecting dopamine pathways. This targeted approach makes it particularly suitable for Parkinson's patients who cannot tolerate medications that block dopamine.

Yes, Pimavanserin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2111101. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 10071196. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C25H34FN3O2
同义词: 1

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.