Prazosin Hydrochloride

CHEMBL1558 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

419.9 g/mol

LogP

—

Phase

4

A hydrochloride salt form of prazosin with the same therapeutic properties. Used to treat high blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood, and is also used off-label to reduce nightmares and sleep disturbances associated with post-traumatic stress disorder.

分子量

419.9000 g/mol

TPSA

107.00 Å²

治疗领域

Benign Prostatic Hyperplasia Cardiovascular Disease Respiratory Disease Pain Management Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Migraine Generalized Anxiety Disorder Insomnia Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Hypertension Chronic Pain Hepatitis C Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC.Cl

InChI

InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H

Molecular Formula

C19H22ClN5O4

HBD / HBA

2 / 8

可旋转键数

4

重原子数

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

A hydrochloride salt form of prazosin with the same therapeutic properties. Used to treat high blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood, and is also used off-label to reduce nightmares and sleep disturbances associated with post-traumatic stress disorder.

Yes, Prazosin Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1558. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 68546. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C19H22ClN5O4

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.