Pyritinol
Pyritinol is a semi-synthetic derivative of pyridoxine (vitamin B6) that is believed to enhance cholinergic neurotransmission and cerebral glucose metabolism, and has been used as a nootropic and neuroprotective agent. It was used for the treatment of cognitive impairment and has been investigated in anxiety disorders, schizophrenia, and rheumatoid arthritis, though it was withdrawn in some countries due to rare but serious adverse effects.
分子量
368.5000 g/mol
LogP
1.20
TPSA
157.00 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
二维结构
Cite this structure
Embed this structure
SMILES
Cc1ncc(CSSCc2cnc(C)c(O)c2CO)c(CO)c1O
InChI
InChI=1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3
Molecular Formula
C16H20N2O4S2
HBD / HBA
4 / 8
可旋转键数
7
重原子数
24
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
Pyritinol is a semi-synthetic derivative of pyridoxine (vitamin B6) that is believed to enhance cholinergic neurotransmission and cerebral glucose metabolism, and has been used as a nootropic and neuroprotective agent. It was used for the treatment of cognitive impairment and has been investigated in anxiety disorders, schizophrenia, and rheumatoid arthritis, though it was withdrawn in some countries due to rare but serious adverse effects.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Pyritinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL488093. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 14190. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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