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Rabeprazole Sodium

CHEMBL1200930 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
381.4 g/mol
LogP
—
Phase
4

The sodium salt form of rabeprazole used to treat GERD and peptic ulcers by significantly reducing the amount of acid the stomach produces. It is typically taken once daily before a meal for effective acid control.

分子量

381.4000 g/mol

TPSA

81.50 Ų

治疗领域

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Asthma Insomnia Infectious Disease Gastroesophageal Reflux Disease Non-Alcoholic Fatty Liver Disease Lymphoma Breast Cancer Atrial Fibrillation Prostate Cancer Colorectal Cancer

作用机制

Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

二维结构

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[n-]2)c1C.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H20N3NaO3S

                    

                    
                    

                        
HBD / HBA

                        
- / 7

                    

                    
                    

                        
可旋转键数

                        
8

                    

                    
                    
                    

                        
重原子数

                        
26

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
The sodium salt form of rabeprazole used to treat GERD and peptic ulcers by significantly reducing the amount of acid the stomach produces. It is typically taken once daily before a meal for effective acid control.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Rabeprazole Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200930.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 14720269.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.