Rezafungin Acetate

CHEMBL3989928 Phase 4 已批准 Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
1285.4 g/mol
LogP
Phase
4

Rezafungin acetate is the acetate salt form of rezafungin, a long-acting echinocandin antifungal that inhibits beta-1,3-D-glucan synthase allowing once-weekly dosing for the treatment of candidemia and invasive candidiasis. See rezafungin for complete pharmacological details.

分子量

1285.4000 g/mol

TPSA

407.00 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

CC(=O)[O-].CCCCCOc1ccc(-c2ccc(-c3ccc(C(=O)N[C@H]4C[C@@H](O)[C@@H](OCC[N+](C)(C)C)NC(=O)[C@@H]5[C@@H](O)[C@@H](C)CN5C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]([C@H](O)[C@@H](O)c5ccc(O)cc5)NC(=O)[C@@H]5C[C@@H](O)CN5C(=O)[C@H]([C@@H](C)O)NC4=O)cc3)cc2)cc1

InChI

InChI=1S/C63H84N8O17.C2H4O2/c1-8-9-10-28-87-45-25-21-40(22-26-45)38-13-11-37(12-14-38)39-15-17-42(18-16-39)56(80)64-46-31-48(76)61(88-29-27-71(5,6)7)68-60(84)52-53(77)34(2)32-70(52)63(86)50(36(4)73)66-59(83)51(55(79)54(78)41-19-23-43(74)24-20-41)67-58(82)47-30-44(75)33-69(47)62(85)49(35(3)72)65-57(46)81;1-2(3)4/h11-26,34-36,44,46-55,61,72-73,75-79H,8-10,27-33H2,1-7H3,(H5-,64,65,66,67,68,74,80,81,82,83,84);1H3,(H,3,4)/t34-,35+,36+,44+,46-,47-,48+,49-,50-,51-,52-,53-,54-,55-,61+;/m0./s1

Molecular Formula

C65H88N8O19

HBD / HBA

13 / 19

可旋转键数

18

重原子数

92

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Rezafungin acetate is the acetate salt form of rezafungin, a long-acting echinocandin antifungal that inhibits beta-1,3-D-glucan synthase allowing once-weekly dosing for the treatment of candidemia and invasive candidiasis. See rezafungin for complete pharmacological details.

Yes, Rezafungin Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989928. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 78318118. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.