Riluzole

CHEMBL744 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

234.2 g/mol

LogP

3.6

Phase

4

A medication used to slow the progression of amyotrophic lateral sclerosis (ALS) by reducing glutamate-mediated nerve damage, and has also been studied in Alzheimer's disease. While it does not cure ALS, it has been shown to modestly extend survival and delay the need for mechanical ventilation.

分子量

234.2000 g/mol

LogP

3.60

TPSA

76.40 Å²

Lipinski 五规则

符合

治疗领域

Melanoma Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Alzheimer's Disease Parkinson's Disease Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Multiple Sclerosis Major Depressive Disorder Breast Cancer Atrial Fibrillation Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

Cite this structure

Embed this structure

SMILES

Nc1nc2ccc(OC(F)(F)F)cc2s1

InChI

InChI=1S/C8H5F3N2OS/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H,(H2,12,13)

Molecular Formula

C8H5F3N2OS

HBD / HBA

1 / 7

可旋转键数

1

重原子数

15

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

A medication used to slow the progression of amyotrophic lateral sclerosis (ALS) by reducing glutamate-mediated nerve damage, and has also been studied in Alzheimer's disease. While it does not cure ALS, it has been shown to modestly extend survival and delay the need for mechanical ventilation.

Yes, Riluzole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL744. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5070. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C8H5F3N2OS
同义词: 2

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.