Rose Bengal Sodium I 131
Rose bengal sodium I-131 is a radioiodinated hepatobiliary imaging agent in which the rose bengal dye is labeled with iodine-131 for scintigraphic evaluation of liver and biliary tract function. It is selectively taken up by hepatocytes and excreted into bile, allowing assessment of hepatic clearance and biliary patency. The compound has also been investigated in experimental oncology for targeted radiotherapy of breast and colorectal cancers.
分子量
1019.6000 g/mol
TPSA
76.00 Ų
治疗领域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
二维结构
Cite this structure
Embed this structure
SMILES
O=C([O-])c1c(Cl)c(Cl)c(Cl)c(Cl)c1-c1c2cc([131I])c(=O)c(I)c-2oc2c(I)c([O-])c([131I])cc12.[Na+].[Na+]
InChI
InChI=1S/C20H4Cl4I4O5.2Na/c21-10-8(9(20(31)32)11(22)13(24)12(10)23)7-3-1-5(25)16(29)14(27)18(3)33-19-4(7)2-6(26)17(30)15(19)28;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2/i25+4,26+4;;
Molecular Formula
C20H4Cl4I4Na2O5+2
HBD / HBA
2 / 5
可旋转键数
0
重原子数
35
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
Rose bengal sodium I-131 is a radioiodinated hepatobiliary imaging agent in which the rose bengal dye is labeled with iodine-131 for scintigraphic evaluation of liver and biliary tract function. It is selectively taken up by hepatocytes and excreted into bile, allowing assessment of hepatic clearance and biliary patency. The compound has also been investigated in experimental oncology for targeted radiotherapy of breast and colorectal cancers.
Yes, Rose Bengal Sodium I 131 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989461. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 22239536. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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