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Sodium Fluoride

CHEMBL1528 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
42.0 g/mol
LogP
—
Phase
4

Sodium fluoride is an inorganic fluoride compound used in dental caries prevention through fluoridation of water supplies and in fluoride supplements, toothpastes, and topical fluoride treatments for remineralization of tooth enamel. Fluoride ions substitute for hydroxyl groups in hydroxyapatite to form fluorapatite, which is more resistant to acid dissolution by oral bacteria. Investigational uses in bone density improvement and as a component of PET imaging agents are under study.

分子量

41.9882 g/mol

TPSA

0.00 Ų

治疗领域

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Cardiovascular Disease Pain Management Ophthalmology Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Chronic Obstructive Pulmonary Disease Schizophrenia Generalized Anxiety Disorder Infectious Disease Nephrology Gastroesophageal Reflux Disease Non-Alcoholic Fatty Liver Disease Stroke Hyperlipidemia Obesity Lymphoma Type 2 Diabetes Breast Cancer Chronic Pain Prostate Cancer Colorectal Cancer

作用机制

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

二维结构

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
[F-].[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/FH.Na/h1H;/q;+1/p-1

                

                

                

                    
                    

                        
Molecular Formula

                        
FNa

                    

                    
                    

                        
HBD / HBA

                        
- / 1

                    

                    
                    

                        
可旋转键数

                        
0

                    

                    
                    
                    

                        
重原子数

                        
2

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
Sodium fluoride is an inorganic fluoride compound used in dental caries prevention through fluoridation of water supplies and in fluoride supplements, toothpastes, and topical fluoride treatments for remineralization of tooth enamel. Fluoride ions substitute for hydroxyl groups in hydroxyapatite to form fluorapatite, which is more resistant to acid dissolution by oral bacteria. Investigational uses in bone density improvement and as a component of PET imaging agents are under study.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Sodium Fluoride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1528.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5235.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.