Sorbitol

CHEMBL1682 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

182.2 g/mol

LogP

-3.1

Phase

4

Sorbitol is a sugar alcohol used as an osmotic laxative, diuretic, humectant, and sweetener in pharmaceutical formulations, and as a vehicle in oral medications and liquid dosage forms. As an osmotic laxative, it draws water into the intestinal lumen to soften stool and stimulate bowel movements, used for constipation and bowel preparation. It is also used as a renal excipient in certain dialysis procedures and as an oral sweetener in diabetic formulations since it is poorly absorbed.

分子量

182.1700 g/mol

LogP

-3.10

TPSA

121.00 Å²

Lipinski 五规则

符合

治疗领域

Glaucoma Cardiovascular Disease Pain Management Generalized Anxiety Disorder Infectious Disease Inflammatory Bowel Disease Systemic Lupus Erythematosus Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Obesity Type 2 Diabetes Hypertension Breast Cancer Chronic Pain Heart Failure Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

Cite this structure

Embed this structure

SMILES

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

Molecular Formula

C6H14O6

HBD / HBA

6 / 6

可旋转键数

5

重原子数

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Sorbitol is a sugar alcohol used as an osmotic laxative, diuretic, humectant, and sweetener in pharmaceutical formulations, and as a vehicle in oral medications and liquid dosage forms. As an osmotic laxative, it draws water into the intestinal lumen to soften stool and stimulate bowel movements, used for constipation and bowel preparation. It is also used as a renal excipient in certain dialysis procedures and as an oral sweetener in diabetic formulations since it is poorly absorbed.

Yes, Sorbitol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1682. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5780. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C6H14O6
同义词: 8

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.