Strontium Chloride Sr 89

CHEMBL1200625 Phase 4 已批准 Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
159.8 g/mol
LogP
Phase
4

Strontium chloride Sr-89 is a beta-emitting radiopharmaceutical used for palliative treatment of bone pain from osteoblastic skeletal metastases in prostate, breast, and other cancers. Strontium-89 is selectively taken up by metabolically active bone at metastatic sites as a calcium analog via active transport by osteoblasts, delivering local beta radiation to reduce pain and tumor burden. The cytotoxic beta emissions have a path length of approximately 8 mm in tissue, limiting radiation to the immediate vicinity of the metastatic lesion.

分子量

159.8100 g/mol

TPSA

0.00 Ų

治疗领域

作用机制

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

二维结构

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SMILES

[89Sr+2].[Cl-].[Cl-]

InChI

InChI=1S/2ClH.Sr/h2*1H;/q;;+2/p-2/i;;1+1

Molecular Formula

Cl2Sr

HBD / HBA

- / 2

可旋转键数

0

重原子数

3

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Strontium chloride Sr-89 is a beta-emitting radiopharmaceutical used for palliative treatment of bone pain from osteoblastic skeletal metastases in prostate, breast, and other cancers. Strontium-89 is selectively taken up by metabolically active bone at metastatic sites as a calcium analog via active transport by osteoblasts, delivering local beta radiation to reduce pain and tumor burden. The cytotoxic beta emissions have a path length of approximately 8 mm in tissue, limiting radiation to the immediate vicinity of the metastatic lesion.

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Yes, Strontium Chloride Sr 89 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200625. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5388879. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.