Strontium Chloride Sr 89
Strontium chloride Sr-89 is a beta-emitting radiopharmaceutical used for palliative treatment of bone pain from osteoblastic skeletal metastases in prostate, breast, and other cancers. Strontium-89 is selectively taken up by metabolically active bone at metastatic sites as a calcium analog via active transport by osteoblasts, delivering local beta radiation to reduce pain and tumor burden. The cytotoxic beta emissions have a path length of approximately 8 mm in tissue, limiting radiation to the immediate vicinity of the metastatic lesion.
分子量
159.8100 g/mol
TPSA
0.00 Ų
治疗领域
作用机制
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
二维结构
Cite this structure
Embed this structure
SMILES
[89Sr+2].[Cl-].[Cl-]
InChI
InChI=1S/2ClH.Sr/h2*1H;/q;;+2/p-2/i;;1+1
Molecular Formula
Cl2Sr
HBD / HBA
- / 2
可旋转键数
0
重原子数
3
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
Strontium chloride Sr-89 is a beta-emitting radiopharmaceutical used for palliative treatment of bone pain from osteoblastic skeletal metastases in prostate, breast, and other cancers. Strontium-89 is selectively taken up by metabolically active bone at metastatic sites as a calcium analog via active transport by osteoblasts, delivering local beta radiation to reduce pain and tumor burden. The cytotoxic beta emissions have a path length of approximately 8 mm in tissue, limiting radiation to the immediate vicinity of the metastatic lesion.
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Yes, Strontium Chloride Sr 89 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200625. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5388879. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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