Thiamine
This is vitamin B1, an essential nutrient that the body needs for energy metabolism and proper functioning of the nervous system and heart. It is used medically to treat or prevent thiamine deficiency, which can cause serious conditions such as beriberi and Wernicke-Korsakoff syndrome, often seen in people with alcohol use disorder or severe malnutrition. It can be taken orally or given by injection in severe cases.
分子量
265.3600 g/mol
LogP
1.00
TPSA
104.00 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
二维结构
Cite this structure
Embed this structure
SMILES
Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1.[Cl-]
InChI
InChI=1S/C12H17N4OS.ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);1H/q+1;/p-1
Molecular Formula
C12H17N4OS+
HBD / HBA
2 / 5
可旋转键数
4
重原子数
18
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
This is vitamin B1, an essential nutrient that the body needs for energy metabolism and proper functioning of the nervous system and heart. It is used medically to treat or prevent thiamine deficiency, which can cause serious conditions such as beriberi and Wernicke-Korsakoff syndrome, often seen in people with alcohol use disorder or severe malnutrition. It can be taken orally or given by injection in severe cases.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Thiamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1588. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 1130. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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