Trimipramine Maleate

CHEMBL1200948 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

410.5 g/mol

LogP

—

Phase

4

Trimipramine maleate is the maleate salt form of trimipramine, a tricyclic antidepressant that blocks serotonin and norepinephrine reuptake transporters while also antagonizing histamine, muscarinic, and dopamine receptors. It is prescribed for depression, anxiety disorders, and sleep disturbances, and has been studied in schizophrenia for its sedative and antipsychotic properties. The maleate salt is used in oral formulations for improved stability.

分子量

410.5000 g/mol

TPSA

81.10 Å²

治疗领域

Schizophrenia Generalized Anxiety Disorder

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

CC(CN(C)C)CN1c2ccccc2CCc2ccccc21.O=C(O)/C=C\C(=O)O

InChI

InChI=1S/C20H26N2.C4H4O4/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;5-3(6)1-2-4(7)8/h4-11,16H,12-15H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

Molecular Formula

C24H30N2O4

HBD / HBA

2 / 6

可旋转键数

6

重原子数

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Trimipramine maleate is the maleate salt form of trimipramine, a tricyclic antidepressant that blocks serotonin and norepinephrine reuptake transporters while also antagonizing histamine, muscarinic, and dopamine receptors. It is prescribed for depression, anxiety disorders, and sleep disturbances, and has been studied in schizophrenia for its sedative and antipsychotic properties. The maleate salt is used in oral formulations for improved stability.

Yes, Trimipramine Maleate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200948. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5282318. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C24H30N2O4

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.