Tripelennamine Hydrochloride

CHEMBL1200446 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

291.8 g/mol

LogP

—

Phase

4

Tripelennamine hydrochloride is the hydrochloride salt of tripelennamine, an ethylenediamine-class H1 antihistamine used to relieve symptoms of allergic rhinitis, urticaria, and other hypersensitivity reactions. It acts by competitively inhibiting histamine at H1 receptors, and its sedative properties result from central H1 blockade. The hydrochloride salt form is used in oral tablet and liquid formulations.

分子量

291.8200 g/mol

TPSA

19.40 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

CN(C)CCN(Cc1ccccc1)c1ccccn1.Cl

InChI

InChI=1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H

Molecular Formula

C16H22ClN3

HBD / HBA

1 / 3

可旋转键数

6

重原子数

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Tripelennamine hydrochloride is the hydrochloride salt of tripelennamine, an ethylenediamine-class H1 antihistamine used to relieve symptoms of allergic rhinitis, urticaria, and other hypersensitivity reactions. It acts by competitively inhibiting histamine at H1 receptors, and its sedative properties result from central H1 blockade. The hydrochloride salt form is used in oral tablet and liquid formulations.

Yes, Tripelennamine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200446. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9066. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C16H22ClN3
同义词: 2

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.