Vutrisiran Sodium

CHEMBL5095303 Phase 4 已批准 Oligonucleotide

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

— g/mol

LogP

—

Phase

4

Vutrisiran sodium is the sodium salt form of vutrisiran, a GalNAc-siRNA therapeutic that silences transthyretin gene expression in hepatocytes to reduce TTR protein production and amyloid formation in hereditary TTR amyloidosis. The sodium salt form is used in the injectable formulation for subcutaneous administration. Quarterly subcutaneous dosing of vutrisiran sodium provides sustained TTR suppression for polyneuropathy management in hATTR amyloidosis.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Vutrisiran sodium is the sodium salt form of vutrisiran, a GalNAc-siRNA therapeutic that silences transthyretin gene expression in hepatocytes to reduce TTR protein production and amyloid formation in hereditary TTR amyloidosis. The sodium salt form is used in the injectable formulation for subcutaneous administration. Quarterly subcutaneous dosing of vutrisiran sodium provides sustained TTR suppression for polyneuropathy management in hATTR amyloidosis.

Yes, Vutrisiran Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Oligonucleotide.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL5095303. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-08-20.

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外部链接

ChEMBL CHEMBL5095303

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.