Candesartan vs Losartan

## Candesartan vs Losartan: Overview

This comparison examines the pharmacological differences between **Candesartan** and **Losartan**.

## Mechanism of Action

**Candesartan**: Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

**Losartan**: Angiotensin II receptor type 1 antagonist.

## Pharmacokinetics

**Half-life**: Candesartan — 9 hours; Losartan — 2 hours.

## Chemical Properties

**Molecular Formula**: Candesartan — C33H34N6O6; Losartan — C22H23ClN6O.

**Molecular Weight**: Candesartan — 610.6640 g/mol; Losartan — 422.9200 g/mol.

**Type**: Candesartan — Small molecule; Losartan — Small molecule.