Candesartan vs Losartan

Candesartan vs Losartan: Overview

This comparison examines the pharmacological differences between Candesartan and Losartan.

Mechanism of Action

Candesartan: Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Losartan: Angiotensin II receptor type 1 antagonist.

Pharmacokinetics

Half-life: Candesartan — 9 hours; Losartan — 2 hours.

Chemical Properties

Molecular Formula: Candesartan — C33H34N6O6; Losartan — C22H23ClN6O.

Molecular Weight: Candesartan — 610.6640 g/mol; Losartan — 422.9200 g/mol.

Type: Candesartan — Small molecule; Losartan — Small molecule.