Captopril vs Cyclosporine

## Captopril vs Cyclosporine: Overview

This comparison examines the pharmacological differences between **Captopril** and **Cyclosporine**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Cyclosporine**: Calcineurin inhibitor suppressing T-cell activation.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Cyclosporine — 6-12 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Cyclosporine — C62H111N11O12.

**Molecular Weight**: Captopril — 217.2850 g/mol; Cyclosporine — 1202.6100 g/mol.

**Type**: Captopril — Small molecule; Cyclosporine — Protein.