Captopril vs Cyclosporine

Captopril vs Cyclosporine: Overview

This comparison examines the pharmacological differences between Captopril and Cyclosporine.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Cyclosporine: Calcineurin inhibitor suppressing T-cell activation.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Cyclosporine — 6-12 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Cyclosporine — C62H111N11O12.

Molecular Weight: Captopril — 217.2850 g/mol; Cyclosporine — 1202.6100 g/mol.

Type: Captopril — Small molecule; Cyclosporine — Protein.