Diltiazem vs Hydrochlorothiazide

## Diltiazem vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Diltiazem** and **Hydrochlorothiazide**.

## Mechanism of Action

**Diltiazem**: Benzothiazepine calcium channel blocker.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Diltiazem — 3-4.5 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Diltiazem — C22H26N2O4S; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Diltiazem — 414.5190 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Diltiazem — Small molecule; Hydrochlorothiazide — Small molecule.