Duloxetine vs Fluoxetine

## Duloxetine vs Fluoxetine: Overview

This comparison examines the pharmacological differences between **Duloxetine** and **Fluoxetine**.

## Mechanism of Action

**Duloxetine**: Serotonin-norepinephrine reuptake inhibitor (SNRI).

**Fluoxetine**: Selective serotonin reuptake inhibitor (SSRI).

## Pharmacokinetics

**Half-life**: Duloxetine — 12 hours; Fluoxetine — 1-3 days.

## Chemical Properties

**Molecular Formula**: Duloxetine — C18H19NOS; Fluoxetine — C17H18F3NO.

**Molecular Weight**: Duloxetine — 297.4150 g/mol; Fluoxetine — 309.3260 g/mol.

**Type**: Duloxetine — Small molecule; Fluoxetine — Small molecule.