Fentanyl vs Lorazepam

## Fentanyl vs Lorazepam: Overview

This comparison examines the pharmacological differences between **Fentanyl** and **Lorazepam**.

## Mechanism of Action

**Fentanyl**: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

**Lorazepam**: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

## Pharmacokinetics

**Half-life**: Fentanyl — 2-4 hours; Lorazepam — 10-20 hours.

## Chemical Properties

**Molecular Formula**: Fentanyl — C22H28N2O; Lorazepam — C15H10Cl2N2O2.

**Molecular Weight**: Fentanyl — 336.4700 g/mol; Lorazepam — 321.1580 g/mol.

**Type**: Fentanyl — Small molecule; Lorazepam — Small molecule.