Fentanyl vs Lorazepam

Fentanyl vs Lorazepam: Overview

This comparison examines the pharmacological differences between Fentanyl and Lorazepam.

Mechanism of Action

Fentanyl: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Lorazepam: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

Pharmacokinetics

Half-life: Fentanyl — 2-4 hours; Lorazepam — 10-20 hours.

Chemical Properties

Molecular Formula: Fentanyl — C22H28N2O; Lorazepam — C15H10Cl2N2O2.

Molecular Weight: Fentanyl — 336.4700 g/mol; Lorazepam — 321.1580 g/mol.

Type: Fentanyl — Small molecule; Lorazepam — Small molecule.