Mefloquine

CHEMBL416956 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
378.3 g/mol
LogP
3.6
Phase
4

An antimalarial medication used to prevent and treat malaria, particularly strains resistant to chloroquine, by disrupting the parasite's ability to break down hemoglobin. It requires careful monitoring due to potential neuropsychiatric side effects.

الوزن الجزيئي

378,3100 g/mol

LogP

3,60

TPSA

45,20 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

OC(c1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12)C1CCCCN1

InChI

InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2

Molecular Formula

C17H16F6N2O

HBD / HBA

2 / 9

الروابط القابلة للدوران

2

الذرات الثقيلة

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

An antimalarial medication used to prevent and treat malaria, particularly strains resistant to chloroquine, by disrupting the parasite's ability to break down hemoglobin. It requires careful monitoring due to potential neuropsychiatric side effects.

Yes, Mefloquine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL416956. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 4046. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.