Mefloquine
An antimalarial medication used to prevent and treat malaria, particularly strains resistant to chloroquine, by disrupting the parasite's ability to break down hemoglobin. It requires careful monitoring due to potential neuropsychiatric side effects.
Molecular Weight
378.3100 g/mol
LogP
3.60
TPSA
45.20 Ų
Lipinski RO5
Pass
Therapeutic Areas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
OC(c1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12)C1CCCCN1
InChI
InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2
Molecular Formula
C17H16F6N2O
HBD / HBA
2 / 9
Rotatable Bonds
2
Heavy Atoms
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
An antimalarial medication used to prevent and treat malaria, particularly strains resistant to chloroquine, by disrupting the parasite's ability to break down hemoglobin. It requires careful monitoring due to potential neuropsychiatric side effects.
Yes, Mefloquine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL416956. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4046. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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