Quinagolide
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist that acts on lactotroph D2 receptors in the pituitary gland to suppress prolactin secretion. It is used for the treatment of hyperprolactinemia including prolactin-secreting adenomas, and has been investigated for its anti-angiogenic properties in endometriosis.
الوزن الجزيئي
395,6000 g/mol
LogP
3,10
TPSA
81,30 Ų
قاعدة ليبينسكي للخمسة
ناجح
المجالات العلاجية
آلية العمل
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
CCCN1CC(NS(=O)(=O)N(CC)CC)CC2Cc3c(O)cccc3CC21
InChI
InChI=1S/C20H33N3O3S/c1-4-10-22-14-17(21-27(25,26)23(5-2)6-3)11-16-12-18-15(13-19(16)22)8-7-9-20(18)24/h7-9,16-17,19,21,24H,4-6,10-14H2,1-3H3
Molecular Formula
C20H33N3O3S
HBD / HBA
2 / 6
الروابط القابلة للدوران
7
الذرات الثقيلة
27
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist that acts on lactotroph D2 receptors in the pituitary gland to suppress prolactin secretion. It is used for the treatment of hyperprolactinemia including prolactin-secreting adenomas, and has been investigated for its anti-angiogenic properties in endometriosis.
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
Yes, Quinagolide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2218861. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3086401. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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