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Quinagolide

CHEMBL2218861 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
395.6 g/mol
LogP
3.1
Phase
4

Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist that acts on lactotroph D2 receptors in the pituitary gland to suppress prolactin secretion. It is used for the treatment of hyperprolactinemia including prolactin-secreting adenomas, and has been investigated for its anti-angiogenic properties in endometriosis.

น้ำหนักโมเลกุล

395.6000 g/mol

LogP

3.10

TPSA

81.30 Ų

Lipinski RO5

ผ่าน

ด้านการรักษา

Endometriosis

กลไกการออกฤทธิ์

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCCN1CC(NS(=O)(=O)N(CC)CC)CC2Cc3c(O)cccc3CC21

                

                

                
                

                    
InChI

                    
InChI=1S/C20H33N3O3S/c1-4-10-22-14-17(21-27(25,26)23(5-2)6-3)11-16-12-18-15(13-19(16)22)8-7-9-20(18)24/h7-9,16-17,19,21,24H,4-6,10-14H2,1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H33N3O3S

                    

                    
                    

                        
HBD / HBA

                        
2 / 6

                    

                    
                    

                        
พันธะที่หมุนได้

                        
7

                    

                    
                    
                    

                        
อะตอมหนัก

                        
27

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist that acts on lactotroph D2 receptors in the pituitary gland to suppress prolactin secretion. It is used for the treatment of hyperprolactinemia including prolactin-secreting adenomas, and has been investigated for its anti-angiogenic properties in endometriosis.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Quinagolide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2218861.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3086401.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.