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Satralizumab

CHEMBL3833307 Phase 4 معتمد Antibody
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Satralizumab is a humanized anti-interleukin-6 receptor (anti-IL-6R) monoclonal antibody used for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in anti-AQP4 antibody-positive patients. By blocking IL-6 signaling, it reduces B-cell-mediated autoimmune pathology and decreases production of pathogenic AQP4-specific antibodies. It is administered subcutaneously and has demonstrated reduction in relapse rates in clinical trials.

المجالات العلاجية

Age-Related Macular Degeneration Hypertension

آلية العمل

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

Satralizumab is a humanized anti-interleukin-6 receptor (anti-IL-6R) monoclonal antibody used for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in anti-AQP4 antibody-positive patients. By blocking IL-6 signaling, it reduces B-cell-mediated autoimmune pathology and decreases production of pathogenic AQP4-specific antibodies. It is administered subcutaneously and has demonstrated reduction in relapse rates in clinical trials.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Satralizumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3833307. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.