Sulfadimethoxine
Sulfadimethoxine is a long-acting sulfonamide antibiotic used in veterinary medicine for treatment of coccidiosis and various bacterial infections, and historically used in human medicine for urinary tract infections and respiratory infections. Its prolonged half-life allows once-daily or less frequent dosing compared to short-acting sulfonamides. Like all sulfonamides, it inhibits dihydropteroate synthase to block bacterial folate synthesis.
الوزن الجزيئي
310,3300 g/mol
LogP
1,60
TPSA
125,00 Ų
قاعدة ليبينسكي للخمسة
ناجح
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1
InChI
InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
Molecular Formula
C12H14N4O4S
HBD / HBA
2 / 8
الروابط القابلة للدوران
5
الذرات الثقيلة
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
Sulfadimethoxine is a long-acting sulfonamide antibiotic used in veterinary medicine for treatment of coccidiosis and various bacterial infections, and historically used in human medicine for urinary tract infections and respiratory infections. Its prolonged half-life allows once-daily or less frequent dosing compared to short-acting sulfonamides. Like all sulfonamides, it inhibits dihydropteroate synthase to block bacterial folate synthesis.
Yes, Sulfadimethoxine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL62193. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5323. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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